RESISTANT Clostridium difficile

[kmattox at aol.com]

A true resistance
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-----Original Message-----
From: "Eduardo Palencia" <palenciahccml at gmail.com>

Date: Fri, 4 Jan 2008 08:50:18 
To:"Trauma &amp, Critical Care mailing list" <trauma-list at trauma.org>
Subject: Re: RESISTANT Clostridium difficile


K, do you refer to an aggresive course, or to a true microbiological
resistance to antimicrobials?

Eduardo

2008/1/4, KMATTOX at aol.com <KMATTOX at aol.com>:
>
> In Houston, particular in the suburbs, cases of SEVERE RESISTANT C.
> Difficile are being seen.    Resistant to both Flagyl
> and  Vancomycin.    WBCs as high
> as 80,000.   Often in  immunosuppressed patients, but not necessarily in
> HIV
> infected  patients.   Seems that the patients are on PPI  drugs.     I am
> aware of the CDC reports and a few of the  recent case reports.    From
> ONE
> hospital in Houston (not mine) I  am aware of 6 cases.      A couple have
> had
> operations  because even after 8 weeks they were still very sick and at
> operation
> they had  thickened large bowel.
>
> I am reporting this for two reasons:
>
> 1.    Have you seen such severe resistance in  C.difficile?
> 2.    If this is a NEW phenomena, then we need to  spread the word.
>
> k
>
>
>
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-- 
Eduardo Palencia Herrejón
Servicio de Medicina Intensiva
Hospital "Infanta Leonor", Vallecas, Madrid, Spain
palenciahccml at gmail.com
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